Posted tagged ‘treatment’

Bye Bye Palladia….Hello BP Medicine

August 25, 2011

Hi everyone.  I have not posted in a while because there was nothing to report.  We have been enjoying time with Rosie.  Everything was status quo until 2 or 3 weeks ago.

One Sunday evening a couple of weeks ago Rosie started acting extremely anxious pacing the rooms, laying down but not getting comfortable and then walking around and pacing again.  She started digging outside which she did not do previously.  It is not like she was digging with a purpose.  She would dig in one direction and then turn around and dig and throw dirt back in the hole she previously dug.  It was more of an obsessive compulsive type of behavior. 

Our normally laid back lab was acting like an extremely stressed out dog.  I emailed the oncologist and she told me to stop the Palladia for a week.  We did that and Rosie’s behavior went back to normal.  The next week we started Palladia again.  After two treatments I noticed that she seemed more anxious but I wasn’t sure.  We gave her the third treatment that Friday and over the weekend she became much more anxious with shallow breathing, racing heartbeat, and pacing around the house and shaking nervously.  I again emailed the oncologist and she said to stop the Palladia again and we brought her in Wednesday for her regular checkup.

Rosie’s blood pressure was very high.  Everything else appeared normal.   The oncologist thinks this is caused by the Palladia.  High blood pressure is one of the side effects of Palladia.   The oncologist prescribed blood pressure medicine for Rosie.  Right now the Palladia is stopped and we are concentrating on bringing her blood pressure down.  I don’t know if the increase in blood pressure is temporary or not.  It is possible Rosie may have to stay on the blood pressure medicine indefinitely.  She said that it is possible, after the blood pressure is stabilized, to go back on Palladia together with blood pressure medicine.  However, at this time I am leaning toward not going back on Palladia.  Rosie has been on it two years and has gained two years of life because of it.   However, these current side effects have scared me.  I am hoping they are not permanent.  Rosie just started the blood pressure medicine yesterday.  So I still see some anxiety.  We go back next week to have her blood pressure checked again.

If your dog is taking Palladia please talk to your oncologist about checking the dog’s blood pressure.  In humans high blood pressure is called “the silent killer.”  In people it often has no symptoms.    Better safe than sorry to have it checked.

Good luck to everyone and I’ll let you know how Rosie’s check up goes.

Update on Rosie’s Palladia and Side Effects

January 31, 2011

Hi everyone!  I wanted to let you know that Rosie is doing great. She restarted Palladia several weeks ago and has had no problem with the side effects like before.  The only thing I have noticed is she sometimes is a little slow getting up when she is lying down. 

It definitely has NOT affected her appetite.  She scarfed down 1/2 of my husband’s pizza in about 2 seconds when he stepped away from the table.  (No, Pizza is NOT on her diet.  She did not seem to care, though.)

She goes back to the veterinary oncologist in a couple of weeks for her regular 6-week checkup.   Taking a break from the Palladia for a week definitely reduced the side effects when she started back.

Starting Palladia Again

September 17, 2010

Rosie got the all clear from her veterinary oncologist.  Her blood protein had bounced back to normal….Yeah!

So, we begin again with the Palladia at the same dosage as she took previously.   However, this time, instead of waiting 6 weeks to check her bloodwork, they will check it in 2 weeks to make sure it is not doing any damage. 

We will keep you posted.

11 Months on Palladia and Still Going

July 31, 2010

Hi everyone.  I thought I would give you an update on Rosie.   For the most part Rosie has been doing great. 

After the July 4th vomiting episode she had a great couple of weeks and then some vomiting after that.  However, it was not nearly as bad as on July 4th.  We stopped the Palladia for a few days and took her to the oncologist.  She was almost due for her regular 6-week check up so we just moved up her appointment a few days.

The oncologist was very happy with how Rosie was doing.  All her bloodwork, liver enzymes, and ultrasound came back normal.  The oncologist said she went over Rosie extremely thoroughly to try to find any lumps and saw none.  She was extremely pleased with the results.  So were we!  The oncologist did not want to adjust the dosage of Palladia for the couple of episodes of vomiting.  She wanted to continue on the current course and see how Rosie does.  Rosie has had 3 Palladia doses since that trip to the oncologist and there have been no problems so far.

In summary, after 11 months Rosie is still cancer free and doing great on Palladia with just a couple of bouts of vomiting, but so far not enough to change the dosage or take her off the Palladia.

That is the latest.  I’ll update you after the next 6 week visit to the oncologist which will be just after Rosie’s 1-year anniversary on Palladia

Rosie is Feeling Better

July 7, 2010

I wanted to give an update to let everyone know that Rosie is feeling better.  She has been back on her regular diet for the last 3 days with no problems.  We restarted the Palladia this evening.  So far so good.  No stomach problems.  So I am guessing it must have been something she ate and not the Palladia that upset her stomach.

10 Months on Palladia and Now She Starts Vomiting?

July 3, 2010

Yes.  Rosie has been on Palladia for just over 10 months with no side effects.  Only once did she experience vomiting and that was early on when I was trying to change her food.  Therefore, I was quite surprised when her dinner and meds came back up last night.

We don’t know what has caused it.  Is it the:

  • Palladia  (Vomiting is one of the side effects.)
  • Mast Cell Tumor (The cancer itself can cause nausea.)
  • Something she ate (Vomiting occurred shortly after her walk.  Did she eat something outside?  Hubby says he didn’t see her eat anything.)

Of course this happens on a Friday night on a holiday weekend when all the regular vets offices are closed.  So I call the nearest 24-emergency clinic and told them what happened and that she was on palladia….and the girl asked me “what’s Palladia.”  I said never mind and called the 24-emergency clinic located at the oncology office.    They said not to give her any food or water for 6 hours and if she is still having symptoms after that to bring her in.  At 4:00 a.m. the next morning she was still having dry heaves. 

At 7:00 a.m. we went to the nearest regular vet’s office and luckily they have facilities to do testing.  So Rosie was seen by the vet, who was very good, and they ran blood work to try to see if possibly the cancer came back and was causing stomach upset.  Everything was in the normal range.  The white blood cell count was at the very lowest end of the range, but still in the normal range.  The vet said that was to be expected for a dog taking chemo.  They gave her 2 shots for nausea and vomiting and told us not to give her any food until this evening.  Only water for today, and then 1/2 her normal meal this evening along with her Prilosec and Metoclopramide for nausea. 

We are back home now.  Rosie is resting.  I’m wondering what she could have eaten that might have caused it.  I was chopping an onion yesterday.  Possibly did a piece fall on the floor and she ate it without me seeing?  Did she manage to convince DH to give her a Chicken and cheese ravioli last night?  DH says he didn’t.  Did she eat something while out on her walk?   We may never know the answer.   We will keep an eye on her this weekend and check with the oncologist on Tuesday when she is back in the office.

Celebration Time!

May 6, 2010

Happy 10th Birthday to Rosie!  She turned 10 on Tuesday this week.  To celebrate, she went to the veterinary oncologist for her 36-week check-up and got a clean bill of health.  Everything was normal including the liver enzymes!  That is an improvement…..And She is STILL CANCER FREE!!!!!!!   The oncology staff even sang “Happy Birthday” to Rosie.  Of course, she loved that.

It has been a busy week but Rosie did get some salmon with her regular dinner.  She loves salmon.  Hopefully, we can do something more for her this weekend.

We have certainly been blessed with Rosie and are fortunate to still have her with us.   She has brought a lot of joy to our lives. 

To those going through difficult times, our thoughts and prayers are with you.  Keep up the good fight.  There are some success stories with happy endings.  Never give up hope.  Good luck to you all.