Posted tagged ‘chemo’

Bye Bye Palladia….Hello BP Medicine

August 25, 2011

Hi everyone.  I have not posted in a while because there was nothing to report.  We have been enjoying time with Rosie.  Everything was status quo until 2 or 3 weeks ago.

One Sunday evening a couple of weeks ago Rosie started acting extremely anxious pacing the rooms, laying down but not getting comfortable and then walking around and pacing again.  She started digging outside which she did not do previously.  It is not like she was digging with a purpose.  She would dig in one direction and then turn around and dig and throw dirt back in the hole she previously dug.  It was more of an obsessive compulsive type of behavior. 

Our normally laid back lab was acting like an extremely stressed out dog.  I emailed the oncologist and she told me to stop the Palladia for a week.  We did that and Rosie’s behavior went back to normal.  The next week we started Palladia again.  After two treatments I noticed that she seemed more anxious but I wasn’t sure.  We gave her the third treatment that Friday and over the weekend she became much more anxious with shallow breathing, racing heartbeat, and pacing around the house and shaking nervously.  I again emailed the oncologist and she said to stop the Palladia again and we brought her in Wednesday for her regular checkup.

Rosie’s blood pressure was very high.  Everything else appeared normal.   The oncologist thinks this is caused by the Palladia.  High blood pressure is one of the side effects of Palladia.   The oncologist prescribed blood pressure medicine for Rosie.  Right now the Palladia is stopped and we are concentrating on bringing her blood pressure down.  I don’t know if the increase in blood pressure is temporary or not.  It is possible Rosie may have to stay on the blood pressure medicine indefinitely.  She said that it is possible, after the blood pressure is stabilized, to go back on Palladia together with blood pressure medicine.  However, at this time I am leaning toward not going back on Palladia.  Rosie has been on it two years and has gained two years of life because of it.   However, these current side effects have scared me.  I am hoping they are not permanent.  Rosie just started the blood pressure medicine yesterday.  So I still see some anxiety.  We go back next week to have her blood pressure checked again.

If your dog is taking Palladia please talk to your oncologist about checking the dog’s blood pressure.  In humans high blood pressure is called “the silent killer.”  In people it often has no symptoms.    Better safe than sorry to have it checked.

Good luck to everyone and I’ll let you know how Rosie’s check up goes.

Rosie Survives Cancer But Risks Her Life Acting Like A Lab

March 24, 2011

My plan was to update everyone on Rosie’s results from her visit to the oncologist.   Any dog on Palladia has to go back to the oncologist or vet every six weeks for bloodwork,  and other tests, and receive an ultrasound every 12 weeks.  So this was one of Rosie’s 12 week visits in which she had all the tests and ultrasound.  In her oncologists words, her bloodwork, ultrasound, and all other tests were “beautiful.”  Everything was normal.   That was music to my ears.  My husband and I were thrilled to hear that.

How does Rosie celebrate?  She went into the back yard and then dug under the storage shed and crawls under it and then gets stuck.  Her collar came off under there; and she almost didn’t get back out.  My husband had to help pull her out.  Thank goodness she didn’t choke, or get cut, or worse.  She scared us to death.

I have been writing all this time about doing everything we can to save our dog’s life by beating this cancer and then she does this!  But dogs will be dogs; and of course she is a lab.  We will be putting cinder blocks under there to try to prevent her from digging.  If anyone has any other ideas, we welcome suggestions.  Also, one of us will always have to be with her in the backyard.

Hope everything is going well for everyone.  Good luck to all of you.

Rosie’s Cancer Survival Tail

February 10, 2011

Yeah….Rosie is doing wonderful and no visible cancer!  She had a great check up with her new oncologist.  Her previous oncologist moved out of state.  Her new oncologist said she saw no concernns re: Rosie’s tests and that she was a “sweetie.”  I agree….but of course I’m not biased!  😉

She has been doing much better.  The hind end weakness is only occasional and not very bad.  It has been much better since we stopped the Palladia for a week.  She has been back on it for 6 weeks and we just received another refill for 6 weeks.  She will go back to the oncologist in another six weeks.  That is the life of a dog on Palladia.  You get to see an oncologist every six weeks.

Our thoughts and prayers are with all of you whose furkids are dealing with the “C” word.  Good luck to all of you.

Update on Rosie’s Palladia and Side Effects

January 31, 2011

Hi everyone!  I wanted to let you know that Rosie is doing great. She restarted Palladia several weeks ago and has had no problem with the side effects like before.  The only thing I have noticed is she sometimes is a little slow getting up when she is lying down. 

It definitely has NOT affected her appetite.  She scarfed down 1/2 of my husband’s pizza in about 2 seconds when he stepped away from the table.  (No, Pizza is NOT on her diet.  She did not seem to care, though.)

She goes back to the veterinary oncologist in a couple of weeks for her regular 6-week checkup.   Taking a break from the Palladia for a week definitely reduced the side effects when she started back.

Starting Palladia Again

September 17, 2010

Rosie got the all clear from her veterinary oncologist.  Her blood protein had bounced back to normal….Yeah!

So, we begin again with the Palladia at the same dosage as she took previously.   However, this time, instead of waiting 6 weeks to check her bloodwork, they will check it in 2 weeks to make sure it is not doing any damage. 

We will keep you posted.

After One Year Rosie’s Palladia is Stopped (For Now)

September 1, 2010

After receiving Palladia for just over a year, Rosie is going to take a 2-week vacation from it.   This was decided with her oncologist after her latest 6-week check-up.  For the last couple of months Rosie has experienced a vomiting episode every couple of weeks and occasional loose stools.  During the first 10 months on Palladia she never experienced vomiting.

For the first time since she started Palladia Rosie’s lab test came back with an abnormality.  Her albumin (a blood protein) had decreased significantly.  So, the oncologist ordered a urinalysis which showed some protein but not enough to explain the entire protein loss.

The liver tests were normal.   The oncologist thinks that Rosie may be losing protein in her GI tract which may be related to the Palladia.   If so, if the Palladia is not stopped in time, it could cause permanent damage.  Therefore, she wants to take a break from the Palladia and check her again in 2 weeks.

A risk is that stopping the Palladia might allow the mast cell tumor with the 20 out of 10 mitotic index to come back.  That would be very bad.  Rosie has already beaten the odds of her diagnosis.  Initially she was only given 2 or 3 months to live after her diagnosis.  Now she has been doing great for a year.

All of this is hard to believe because if you look at Rosie she looks great!  You would not know she was dealing with something this serious.  Rosie has not acted sick.  She is happy, playful, and will eat as much food as you will give her.  She might get a little vomiting every few weeks but otherwise seemed fine.

So, I hope her blood proteins bounce back.  I would feel horrible if we did not stop the Palladia in time and caused permanent damage.  

We hope and pray that Rosie’s blood proteins will improve and that the cancer stays away.  I’ll post an update in a couple of weeks.

11 Months on Palladia and Still Going

July 31, 2010

Hi everyone.  I thought I would give you an update on Rosie.   For the most part Rosie has been doing great. 

After the July 4th vomiting episode she had a great couple of weeks and then some vomiting after that.  However, it was not nearly as bad as on July 4th.  We stopped the Palladia for a few days and took her to the oncologist.  She was almost due for her regular 6-week check up so we just moved up her appointment a few days.

The oncologist was very happy with how Rosie was doing.  All her bloodwork, liver enzymes, and ultrasound came back normal.  The oncologist said she went over Rosie extremely thoroughly to try to find any lumps and saw none.  She was extremely pleased with the results.  So were we!  The oncologist did not want to adjust the dosage of Palladia for the couple of episodes of vomiting.  She wanted to continue on the current course and see how Rosie does.  Rosie has had 3 Palladia doses since that trip to the oncologist and there have been no problems so far.

In summary, after 11 months Rosie is still cancer free and doing great on Palladia with just a couple of bouts of vomiting, but so far not enough to change the dosage or take her off the Palladia.

That is the latest.  I’ll update you after the next 6 week visit to the oncologist which will be just after Rosie’s 1-year anniversary on Palladia