10 Months on Palladia and Now She Starts Vomiting?

Yes.  Rosie has been on Palladia for just over 10 months with no side effects.  Only once did she experience vomiting and that was early on when I was trying to change her food.  Therefore, I was quite surprised when her dinner and meds came back up last night.

We don’t know what has caused it.  Is it the:

  • Palladia  (Vomiting is one of the side effects.)
  • Mast Cell Tumor (The cancer itself can cause nausea.)
  • Something she ate (Vomiting occurred shortly after her walk.  Did she eat something outside?  Hubby says he didn’t see her eat anything.)

Of course this happens on a Friday night on a holiday weekend when all the regular vets offices are closed.  So I call the nearest 24-emergency clinic and told them what happened and that she was on palladia….and the girl asked me “what’s Palladia.”  I said never mind and called the 24-emergency clinic located at the oncology office.    They said not to give her any food or water for 6 hours and if she is still having symptoms after that to bring her in.  At 4:00 a.m. the next morning she was still having dry heaves. 

At 7:00 a.m. we went to the nearest regular vet’s office and luckily they have facilities to do testing.  So Rosie was seen by the vet, who was very good, and they ran blood work to try to see if possibly the cancer came back and was causing stomach upset.  Everything was in the normal range.  The white blood cell count was at the very lowest end of the range, but still in the normal range.  The vet said that was to be expected for a dog taking chemo.  They gave her 2 shots for nausea and vomiting and told us not to give her any food until this evening.  Only water for today, and then 1/2 her normal meal this evening along with her Prilosec and Metoclopramide for nausea. 

We are back home now.  Rosie is resting.  I’m wondering what she could have eaten that might have caused it.  I was chopping an onion yesterday.  Possibly did a piece fall on the floor and she ate it without me seeing?  Did she manage to convince DH to give her a Chicken and cheese ravioli last night?  DH says he didn’t.  Did she eat something while out on her walk?   We may never know the answer.   We will keep an eye on her this weekend and check with the oncologist on Tuesday when she is back in the office.

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7 Comments on “10 Months on Palladia and Now She Starts Vomiting?”

  1. Anne Laskin Says:

    I am sorry to hear that Rosie is not feeling well. I understand your wading through all the possibilities and still not being sure what has caused this. Sounds like you are managing this as well as possible and I pray she continues to recover.

    My dog Hunter has several mast cell tumors and when they are reacting to the Palladia, they release so much histamine. We live in the country and the nearest oncologist is a 2 hour drive. Our country vet is using Palladia for the first time because I insisted on it but her staff are not helpful and the vet has been away more than available recently. So I understand having a sick dog without much veterinary support.

    I was told last Monday by our veterinarian’s staff member by telephone to stop the Palladia because Hunter’s WBC was low. My vet has been away all week. Of course I haven’t been able to get a copy of the report. I’m a nurse practitioner and understand how to read lab reports. Since I’ve stopped the Palladia I can see the tumors beginning to reform and enlarge.

    Since it is a holiday weekend, maybe Rosie did get hold of something she shouldn’t have eaten. I too have a family member that likes to “sneak” special treats to our sick dog.

    Best to you and Rosie.

    • rosiesmom Says:

      Thanks for your reply, Anne. It is tough when a dog is sick and the vets are not available. There are 24 hour animal clinics here but when I went online to read reviews, they all received terrible reviews. So I waited until a regular vet I trusted was open. Luckily I had to wait only a few hours.

      Good luck to you and hunter. I hope he gets better. Maybe the oncologist will have another treatment option.

      Rosies Mom

  2. C D Orr Says:

    Oh my, I hope Rosie’s vomiting stops and she is okay. I have been following her progress with interest and I so want to see Palladia help her and have her flourish and live for a long while yet.

    My little dog was on Palladia for 4 months and was tolerating it very well, but, unhappily, the cancer returned and he passed away last month.

    Fingers crossed for Rosie!

    • rosiesmom Says:

      I’m so sorry for your loss. You have my deepest sympathy.

      The good news is that Rosie seems to be feeling somewhat better this evening. So far she has kept down her medicine and small meal. Will keep you posted on her progress.

  3. Amy Says:

    I was sorry to see your latest post, but glad to hear she’s feeling good enough to eat. When Katie wasn’t feeling well I would give her organic cottage cheese and she really seemed to like it.
    We had a similar situation with lomustine and plummeting WBC count. It was very scary and the local emergency vet had no knowledge of chemo – we would have lost her that night had we not taken her to another emergency vet with a more knowledgeable vet.
    I hope Rosie’s tummy continues to improve – give her lots of love!

    • rosiesmom Says:

      Thanks Amy. Rosie seems to be feeling better. We gave her a small meal last night and 2 small meals today so far. She has kept everything down and has been sniffing around for more food.

      I think it must have been something she ate, but will contact the oncologist just in case.

  4. David Says:

    I am happy that I found your site. My dog had surgery today for a mastic tumor. Type II. I had no hope after seeing your site I feel that she has a chance. She is an 11 year old Weimaraner. A ton of energy at 11. She did an 8 mile hike for her birthday on saturday. The love of my life. Thank you for giving people hope. I hope my dog is the fighter Rosie is. I believe she is.

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